Category: Microfluidics for biology

Over the last few years, there have been major developments in organ-on-chip (OoC) platforms. Yet, there is no ‘one-fits-all’ model, and probably will never be considering the variety of applications for which those devices can be used. Thus, it is...

What are organ-on-chips? Organ-on-chips (OoC) or Micro-Physiological Systems (MPS) are microfluidic systems that allow the growth of cells to model biological tissues. These platforms combine a multicellular environment with a 2D or 3D structure and mechanical cues to mimic the...

The search for ultra-transparent material to manufacture microfluidic chips is not a coincidence. The ultra-transparency of the materials lends itself very well to microscopy, especially for biological applications. In this short review, our expert team presents a simple protocol for...

By combining the principles of microfluidics, microfabrication, and cell culturing techniques, a new generation of laboratory platforms has emerged, known as “organ-on-chip”. Organ-on-chip systems are microfluidic devices containing living cells. These microfluidic devices can better recapitulate microenvironments compared to previous...

Generally, hydrogels have been utilized as scaffold materials for the immobilization of cells in a microfluidic chip. Different strategies have been employed for the preparation of three-dimensional cell-hydrogel scaffolds. In this review, we discuss the main hydrogels that can be...

The use of microfluidics in biology and medicine offers exciting new possibilities for in-vitro cell culture thanks to increased control in the microenvironment of the cells. Two important and connected topics emerging in this field are organ on chip and...

Microfluidic chips can provide a biomimetic environment for cell and tissue culture, preserving key aspects of the biological system while integrating downstream analysis. It is even possible to go further by integrating a continuous supply of nutrients via recirculation of...

Microfluidic-based hydrodynamic trap facilitates trapping using the sole action of fluid flow and provides a viable alternative to existing confinement and manipulation techniques based on electric, optical, magnetic or acoustic force fields for example. In this review, we describe various...

Liver plays a fundamental role in metabolic activities such as the regulation of glucose levels in the blood, production of plasma proteins, drug metabolism, production of bile [1][2] and presents a complex structure from a morphological and functional point of...

With the increase of cell culture chips and organs-on-chips, sterilization is essential in microfluidics for any equipment in contact with sensitive fluids. Many processes exist, but the autoclave (or steam sterilizer) remains the most common technique thanks to its low...