When selecting tubing for microfluidic applications, ensuring chemical compatibility is crucial for maintaining system integrity and performance. Tygon XL-60 tubing is an ultra-flexible choice for peristaltic pump applications, renowned for its exceptional chemical resistance and longevity. Its formulation provides a service life of over 500 hours at 600 rpm (1000 hours at 100 rpm), with an ultra-smooth inner bore ensuring reliable performance even in the presence of acids, bases, and various chemicals. These attributes make it a preferred choice for applications requiring both durability and broad chemical compatibility.
However, like all materials, Tygon XL-60 has its limitations, and not every chemical is compatible with it. Therefore, understanding compatibility is essential for preventing tubing degradation and ensuring safety. In this guide, we present a comprehensive table of chemical compatibility for Tygon XL-60. This table, based on the chemical compatibility data (at 23°C) provided by Saint-Gobain, is designed to help engineers, technicians, and researchers quickly determine whether Tygon XL-60 tubing is suitable for their specific applications, ensuring reliable and long-lasting performance in diverse chemical environments.
Refer to this table to make informed choices and maintain the efficiency and safety of your system.
💡 The chemical compatibility rating key is as follows:
- E = Excellent chemical compatibility (no effect)
- G = Good chemical compatibility (minor effect: slight corrosion or discoloration)
- F = Fair (moderate effect: not recommended for continuous use; softening, loss of strength, swelling and/or shrinkage)
- X = Severe effect (not recommended for use; severe softening, swelling and/or shrinkage)
- w = Water
- alc = Alcohol
- % = Concentration (If concentration is not indicated, assume 100% concentration or the maximum percent solubility in water)
🚨Concentrations of room temperature liquids are given in % volume. Concentrations of room temperature solids are given in % weight.
🚨 The compatibility ratings provided in these tables are for general guidance only and may not be complete or accurate. They do not address potential contamination or changes in fluid properties due to tubing interaction. We do not guarantee the suitability of any material for specific purposes or the impact of tubing on fluid quality. For critical applications, conduct specific tests or seek expert advice.
Tygon XL-60 Tubing: Chemical Compatibility Table
| Chemical Substance | Compatibility |
|---|---|
| A | |
| Acetaldehyde | F |
| Acetamide, 67% in w | G |
| Acetate Solvents (general) | X |
| Acetic Acid, 10% in w | E |
| Acetic Acid, 50-60% in w | E |
| Acetic Acid, Glacial, 100% | F |
| Acetic Anhydride | E |
| Acetone | X |
| Acetonitrile | X |
| Acetyl Bromide | F |
| Acetyl Chloride | F |
| Acetylene Gas | E |
| Acrylonitrile | X |
| Adipic Acid, 100% in alc | F |
| Air | E |
| Alcohols General | F |
| Aliphatic Hydrocarbons | X |
| Allyl Alcohol | F |
| Alum, 5% in w | E |
| Aluminum Chloride, 53% in w | E |
| Aluminum Hydroxide, 2% in w | E |
| Aluminum Salts | E |
| Aluminum Sulfate, 50% in w | E |
| Amines | F |
| Ammonia Gas | E |
| Ammonia, Anhydrous Liquid | E |
| Ammonium Acetate, 45% in w | E |
| Ammonium Carbonate, 50% in w | E |
| Ammonium Hydroxide, 5-10% n w | E |
| Ammonium Hydroxide, 30% in w | E |
| Ammonium Persulfate, 30% in w | E |
| Ammonium Salts | E |
| Ammonium Sulfate, 30% in w | E |
| Amyl Acetate | X |
| Amyl Alcohol | X |
| Amyl Chloride | X |
| Aniline | X |
| Aniline Hydrochloride | X |
| Antimony Salts | E |
| Aqua Regia | E |
| Aromatic Hydrocarbons | X |
| Arsenic Acid, 20% in w | F |
| Arsenic Salts | E |
| ASTM Reference No. 1 Oil | X |
| ASTM Reference No. 2 Oil | X |
| ASTM Reference No. 3 Oil | X |
| B | |
| Barium Carbonate, 1% in w | E |
| Barium Hydroxide, 5% in w | E |
| Beer | E |
| Benzaldehyde | X |
| Benzene | X |
| Benzenesulfonic Acid | E |
| Benzoic Acid | X |
| Benzyl Alcohol | X |
| Bleach Liquor, 22% in w | E |
| Borax, 6% in w | E |
| Boric Acid, 4% in w | E |
| Bromine, Anhydrous Liquid | X |
| Butadiene | E |
| Butane | E |
| Butyl Acetate | X |
| Butyl Alcohol | E |
| Butyric Acid | E |
| C | |
| Calcium Carbonate, 25% in dilute acids | E |
| Calcium Chloride, 30% in w | E |
| Calcium Hydroxide, 10% in glycerol | E |
| Calcium Hypochlorite, 20% in w | E |
| Calcium Nitrate, 55% in w | E |
| Calcium Salts | E |
| Calcium Sulfate, 1% in w | E |
| Carbon Dioxide, Wet/Dry | E |
| Carbon Disulfide | X |
| Carbon Monoxide | E |
| Carbon Tetrachloride | X |
| Carbonic Acid | E |
| Castor Oil | F |
| Cellosolve | X |
| Cellosolve Acetate | X |
| Chlorine, Dry Gas | G |
| Chlorine, Wet Gas | F |
| Chloroacetic Acid, 20% in w | E |
| Chlorobenzene, Mono, Di, Tri | X |
| Chloroform | X |
| Chlorosulfonic Acid | E |
| Chromic Acid, 10-20% in w | E |
| Chromic Acid, 50% in w | G |
| Citric Acid, 10-20% in w | E |
| Coconut Oil | F |
| Corn Syrup | G |
| Cottonseed Oil | F |
| Cresol (m, o, or p) | X |
| Cresylic Acid | X |
| Cupric Chloride, 40% in w | E |
| Cupric Nitrate, 70% in w | E |
| Cupric Sulfate, 13% in w | E |
| Cyclohexane | X |
| Cyclohexanone | X |
| D | |
| Detergent Solutions | G |
| Dibutyl Phthalate | F |
| Diesel Fuel | X |
| Diethylamine, 2.5% in w | E |
| Diethylene Glycol | E |
| Dimethylformamide | E |
| Dimethylsulfoxide (DMSO) | X |
| Dioctyl Phthalate | F |
| Dioxane | X |
| E | |
| Ether | X |
| Ethyl Acetate | E |
| Ethyl Alcohol (Ethanol) | E |
| Ethyl Benzoate | X |
| Ethyl Chloride | E |
| Ethyl Ether | X |
| Ethylene Bromide | X |
| Ethylene Chlorohydrin | E |
| Ethylene Dichloride | E |
| Ethylene Glycol | E |
| Ethylene Oxide | E |
| F | |
| Fatty Acids | E |
| Ferric Chloride, 43% in w | E |
| Ferric Nitrate, 60% in w | E |
| Ferric Sulfate, 5% in w | E |
| Ferrous Chloride, 40% in w | E |
| Ferrous Sulfate, 5% in w | E |
| Fluoboric Acid, 48% in w | E |
| Fluorine Gas | X |
| Fluosilicic Acid, 25% in w | E |
| Formaldehyde, 37% in w | E |
| Formic Acid, 25% in w | E |
| Formic Acid, 40-50% in w | E |
| Formic Acid, 98% in w | E |
| Freon 11 | G |
| Freon 12 | G |
| Freon 22 | G |
| Fruit Juice | E |
| Fuel Oil | X |
| Furfural | X |
| G | |
| Gallic Acid, 17% in acetone | X |
| Gasoline, Automotive | X |
| Gelatin | E |
| Glucose, 50% in w | E |
| Glycerol, (Glycerin) | E |
| Glycolic Acid, 70% in w | G |
| H | |
| Heptane | X |
| Hexane | X |
| Hydrazine | X |
| Hydrobromic Acid, 100% in w | E |
| Hydrobromic Acid, 20-50% in w | E |
| Hydrochloric Acid, 10% in w | E |
| Hydrochloric Acid, 37% in w | E |
| Hydrocyanic Acid | E |
| Hydrofluoric Acid, 10% in w | E |
| Hydrofluoric Acid, 25% in w | E |
| Hydrofluoric Acid, 40-48% in w | E |
| Hydrogen Gas | E |
| Hydrogen Peroxide, 10% in w | E |
| Hydrogen Peroxide, 3% in w | E |
| Hydrogen Peroxide, 30% in w | E |
| Hydrogen Peroxide, 90% in w | E |
| Hydrogen Sulfide | E |
| Hydroquinone, 7% in w | G |
| Hypochlorous Acid, 25% in w | E |
| I | |
| Iodine, 50 ppm in w | E |
| Isobutyl Alcohol | F |
| Isooctane | X |
| Isopropyl Acetate | X |
| Isopropyl Alcohol | F |
| Isopropyl Ether | X |
| J | |
| Jet Fuel, JP8 | X |
| K | |
| Kerosene | X |
| Ketones | X |
| L | |
| Lacquer Solvents | X |
| Lactic Acid, 3-10% in w | E |
| Lactic Acid, 85% in w | E |
| Lard, Animal Fat | F |
| Lead Acetate, 35% in w | E |
| Lead Salts | E |
| Lemon Oil | X |
| Limonene-D | X |
| Linoleic Acid | F |
| Linseed Oil | X |
| Lubricating Oils, Petroleum | X |
| M | |
| Magnesium Carbonate, 1% in w | E |
| Magnesium Chloride, 35% in w | E |
| Magnesium Hydroxide, 10% in dil. acid | E |
| Magnesium Nitrate, 50% in w | E |
| Magnesium Sulfate, 25% in w | E |
| Maleic Acid, 30% in w | F |
| Malic Acid, 36% in w | E |
| Manganese Salts | E |
| Mercuric Chloride, 6% in w | E |
| Mercuric Cyanide, 8% in w | E |
| Mercury | E |
| Mercury Salts | E |
| Methane Gas | E |
| Methyl Acetate | X |
| Methyl Alcohol (Methanol) | X |
| Methyl Bromide | X |
| Methyl Chloride | X |
| Methyl Ethyl Ketone (MEK) | X |
| Methyl Isobutyl Ketone | X |
| Methyl Methacrylate | X |
| Methylene Chloride | X |
| Milk | E |
| Mineral Oil | F |
| Mineral Spirits | X |
| Molasses | E |
| Monoethanolamine | E |
| Motor Oil | X |
| N | |
| Naphtha | X |
| Naphthalene | X |
| Natural Gas | E |
| Nickel Chloride, 40% in w | E |
| Nickel Nitrate, 75% in w | E |
| Nickel Salts | E |
| Nickel Sulfate, 25% in w | E |
| Nitric Acid, 10% in w | E |
| Nitric Acid, 35% in w | E |
| Nitric Acid, 68-71% in w | E |
| Nitrobenzene | X |
| Nitromethane | X |
| Nitrous Acid, 10% in w | E |
| Nitrous Oxide | E |
| O | |
| Oils, Animal | F |
| Oils, Essential | X |
| Oils, Hydraulic (Phosphate Ester) | X |
| Oils, Hydrocarbon | X |
| Oils, Vegetable | F |
| Oleic Acid | F |
| Oleum, 25% in w | G |
| Ortho Dichlorobenzene | X |
| Oxalic Acid, 12% in w | E |
| Oxygen | E |
| Ozone, 300pphm | E |
| P | |
| Palmitic Acid, 100% in ether | X |
| Paraffins | X |
| Perchloric Acid, 67% in w | E |
| Perchloroethylene | F |
| Phenol, 5-10% in w | X |
| Phenol, 91% in w | X |
| Phosphoric Acid, | E |
| Phosphoric Acid, 25% in w | E |
| Phosphoric Acid, 85% in w | G |
| Phosphorous Trichloride Acid | G |
| Photographic Solutions | G |
| Phthalic Acid, 9% in alc | X |
| Phthalic Anhydride, 9% in alc | G |
| Picric Acid, 1% in w | X |
| Plating Solutions | G |
| Potassium Carbonate, 55% in w | E |
| Potassium Cyanide, 33% in w | E |
| Potassium Dichromate, 5% in w | E |
| Potassium Hydroxide, | E |
| Potassium Hypochlorite, 70% in w | G |
| Potassium Iodide, 56% in w | E |
| Potassium Permanganate, 6% in w | E |
| Potassium Salts | E |
| Propane Gas | E |
| Propyl Alcohol (Propanol) | F |
| Propylene Glycol | E |
| Propylene Oxide | E |
| Pyridine | E |
| S | |
| Salicylic Acid, 1% in w | E |
| Silicone Oils | E |
| Silver Nitrate, 55% in w | E |
| Skydrol 500A | X |
| Soap Solutions | E |
| Sodium Acetate, 55% in w | E |
| Sodium Benzoate, 22% in w | E |
| Sodium Bicarbonate, 7% in w | E |
| Sodium Carbonate, 7% in w | E |
| Sodium Chlorate, 45% in w | E |
| Sodium Chloride, 20% in w | E |
| Sodium Cyanide, 30% in w | E |
| Sodium Fluoride, 3% in w | E |
| Sodium Hydroxide, 10-15% in w | E |
| Sodium Hydroxide, 2-5% in w | E |
| Sodium Hydroxide, 30-40% in w | E |
| Sodium Hypochlorite, 12.2% in w | E |
| Sodium Hypochlorite, 5.5% in w | E |
| Sodium Nitrate, 3.5% in w | E |
| Sodium Salts | E |
| Sodium Sulfate, 5% in w | E |
| Sodium Sulfide, 45% in w | E |
| Sodium Sulfite, 10% in w | E |
| Stannic Chloride, 50% in w | E |
| Stannous Chloride, 45% in w | E |
| Stearic Acid, 5% in alc | E |
| Styrene Monomer | X |
| Sulfur Chloride | E |
| Sulfur Dioxide, Gas Dry | E |
| Sulfur Dioxide, Gas Wet | E |
| Sulfur Trioxide, Wet | E |
| Sulfuric Acid, 10% in w | E |
| Sulfuric Acid, 30% in w | E |
| Sulfuric Acid, 95-98% in w | E |
| Sulfurous Acid | E |
| T | |
| Tannic Acid, 75% in w | E |
| Tartaric Acid, 56% in w | E |
| Tetrahydrofuran | X |
| Thionyl Chloride | E |
| Tin Salts | E |
| Titanium Salts | E |
| Toluene | X |
| Trichloroacetic Acid, 90% in w | E |
| Trichloroethane | X |
| Triethanolamine | X |
| Trichloroethylene | X |
| Trichloropropane | X |
| Tricresyl Phosphate | G |
| Trisodium Phosphate | E |
| Turpentine | X |
| U | |
| Urea, 20% in w | E |
| Uric Acid | E |
| V | |
| Vinegar | E |
| Vinyl Acetate | X |
| W | |
| Water, Deionized | E |
| Water, Distilled | E |
| X | |
| Xylene | X |
| Z | |
| Zinc Chloride, 80% in w | E |
| Zinc Salts | E |
